Custom DNA Oligos

Macrogen provides the best oligo synthesis service with the latest equipment and an automated system.

High-quality oligos are produced via a purification process by removing impurities and oligos that are nonspecifically bound. The quality of all oligos is controlled by MALDI-TOF mass spectrometry.

Features

  • - Scales from 0.025 µmole to 1 µmole
  • - Quick delivery by express courier (using FedEx / DHL International shipping)
  • - Accurate concentration provided by the liquid handling system
  • - Orders, progress of synthesis, delivery, and results of synthesis can be confirmed by Laboratory Information Management System (LIMS)
  • - Duplex oligos (double-stranded oligos) are possible
  • - Free shipping: ≥ 300 bases of primers

Guaranteed Yield

  • Standard oligos can be synthesized for 3 ~ 130 mer
  • For modified oligos, up to 60 mer is recommended (Inquire for oligos of 60 mer or more)
Guaranteed Yield (OD) Synthesis Scale
0.025 0.05 0.2 1
Desalt 3 - - -
MOPC - 6 8 20
PAGE - 2 4 8
HPLC - 2 4 8

Oligo Synthesis Purification

Salt Free(Desalt) MOPC (Macrogen Oligonucleotide
Purification Cartridge)
HPLC PAGE
  • - Available for unmodified oligos (0.025 µmole)
  • - Length from 3~35mer
  • - Available for both standard oligos and some modified oligos
  • - Purity of ≥85% (LC analysis)
  • - Available for free as a default for all oligos
  • - Available for all standard oligos and modified oligos
  • - Recommended for oligos of 50 mer or less
  • - Purity of ≥ 90% (LC analysis)
  • - Available for all standard oligos and modified oligos
  • - Recommended for oligos of 50 mer or less
  • - purity of ≥95% (LC analysis)

100% QC

Release and delivery of synthesized oligos occur after OD measurement and MALDI-TOF MS analysis to ensure quality. The result report is shipped with the ordered oligos.

The MALDI-TOF molecular weight analysis method, which is more accurate than PAGE gel QC, is used as the quality check method for oligos and precisely analyzes oligos containing N-1 and N-2.