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Together with the IT sector, biotechnology
has become the new growth engine that drives the
future economy beyond the scope of science. Scientific
technology, which had always pursued the convenience
of human life, now seeks the improvement of the
quality of human life. Since then, global efforts
have been exerted to solve the mystery of life and
provide solutions to various types of diseases.
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The results obtained through such efforts
are used for alternate solutions to problems facing the
society such as famine and ecological threats; hence the
emphasis and growing recognition of molecular/cell biology
as the basis of biotechnology.
The future of Korea’s national economy lies heavily on
young and talented life scientists.
The newly established “Macrogen Young Scientist Award”
is given every year in recognition of young Korean scientists
with outstanding achievements in the field of biology.
Compared with advanced countries, our start was rather
late. As long as there are young scientists who devote
themselves to various fields, however, Korea shall not
lag behind any country in terms of the growth potential
of domestic biotechnology. As a leader in the domestic
bio industry, which assumes responsibility for the development
of Korea’s biotechnology, Macrogen wishes to encourage
our young scientists and contribute, albeit a little,
to the development of domestic life sciences through the
establishment of this award.
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[2nd award recipient]
Professor Sung Hee Baek, Life
Sciences Dep't of Seoul National University |
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1. Kim, J. H., Kim,
B., Ling, C., Choi, H. J., Ohgi, K. A., Tran, C,
Chen, C., Chung, C. H., Huber, |
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O., Rose, D. W., Sawyers,
C. L., Rosenfeld, M. G., and Baek, S. H.
Transcriptional regulation |
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of a metastasis suppressor
gene by Tip60 and b-Catenin Complexes. Nature (2005) 434,
921-926. |
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2. Lee, Y., Kim, M.,
Han, J., Yeom, K. H., Lee, S., Baek, S. H., and
Kim, V. N. MicroRNA genes |
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are transcribed by RNA
polymerase II. EMBO J. (2004) 23, 4051-4060. |
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3. Chen, C. D. Welsbie,
D. S., Tran, C., Baek, S. H., Chen, R., Vessella,
R., Rosenfeld, M. G., and |
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Sawyers, C. L.
Molecular determinants of resistance to anti-androgen
receptor therapy. |
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Nature Medicine (2004) 10,
33-39. |
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4. Gold, D. A., Baek,
S. H., Schork, N. J., Larsen, D. D., Rosenfeld,
M. G., Hamilton, B. A. (2003) |
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ROR? coordinates reciprocal
signaling events in cerebellar development through
sonic hedgehog and |
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calcium-dependent pathways.
Neuron (2003) 40, 1119-1131. |
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5. Baek, S. H., Kioussi,
C., Briata, P., Wang, D., Nguyen, H. D., Ohgi, K.
A., Glass, C. K., |
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Wynshaw-Boris, A., Rose,
D. W., and Rosenfeld, M. G. Regulated subset
of G1 growth-control |
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genes in response to
derepression by the Wnt Pathway. Proc. Natl. Acad.
Sci. USA (2003) 100, 3245-3250. |
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6. Baek, S. H.*, Kioussi,
C.*, Briata, P.*, Rose, D. W.*, Hamblet, N. S.,
Herman, T., Ruiz-Lozano, |
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P., Lin, C., Gleiberman,
A., Wang, J., Wang, D., Glass, C. K., Wynshaw-Boris,
A., and Rosenfeld, |
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M. G. (*cofirst author)
Identification of a Wnt/Dvl/beta-catenin
to Pitx2 pathway reveals |
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molecular mechanisms
for mediating cell type-specifc proliferation during
development. |
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Cell (2002) 111: 673-685. |
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7. Baek, S. H., Ohgi,
K. A., Rose, D. W., Koo, E. H., Glass, C. K., and
Rosenfeld, M. G. |
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Exchange of N-CoR corepressor
and Tip60 coactivator complexes links gene expression
by |
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NF-(B and (-amyloid
precursor protein. Cell (2002) 110. 55-67. |
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8. Dasen, J. S., Barbera,
J. P., Herman, T. S., Connell, S. O., Olson, L.,
Ju, B., Tollkuhn, J., Baek, |
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S. H., Rose, D. W.,
and Rosenfeld, M. G. Temporal regulation
of a paired-like homeodomain |
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repressor/TLE corepressor
complex and a related activator is required for
pituitary organogenesis. |
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Genes & Dev. (2001) 15.
3193-3207. |
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